Bacognize® extract is a natural standardized formula derived from Bacopa monnieri. Clinical research indicates that Bacognize® may offer benefits for cognitive health linked to three major neuroprotective mechanisms; including neurotransmitter receptor (serotonin) binding activity and antioxidant capacity. Bacopa is commonly used as an adaptogen supporting cognitive enhancement, memory, focus, attention, mood, emotional health, and stress.
EpiCor® is a, clinically researched fermentate shown to support the immune system for better overall health.
Ester-C® is a unique and patented form of Calcium Ascorbate-Threonate. It is made using a proprietary, water-based manufacturing process which results in a pH neutral product that contains naturally occurring vitamin C metabolites.
The main benefit of Ester-C® is its quick absorption and 24-hour retention in the immune system.
Ester-C Calcium Ascorbate-Threonate is approved by EFSA on Annex II and therefore allowed for use in food supplements. EFSA Claims for Vitamin C can be used for Ester-C with the benefits and advantages of this patented product.
|The Ester C Company|
|GlucosaGreen||TSI is a world-class manufacturer of innovative and functional health products, one of them being their vegan glucosamine GlucosaGreen®. TSI strives to create the highest quality products to maximize and maintain active, healthy lifestyles for consumers.|
GlucosaGreen® is an environmentally friendly, vegan range of glucosamine salts, produced by a patented protected fermentation process. GlucosaGreen® is a convenient and sustainable alternative to shellfish glucosamine. The direct ferrmentation process to produce GlucosaGreen® generates significantly less wastewater and only 2% of the solid waste compared to chitin glucosamine manufacturing. Furthermore, a chitin-free supply chain provides price stability and full traceability.
GlucosaGreen® vs Traditional Glucosamine: Producing 1 metric ton of chitin-derived glucosamine HCl creates approximately 450-460 metric tons of wastewater and 5 - 6 metric tons of solid waste. This wastewater contains potentially harmful (especially to aquatic life) pH levels (5.5), Chemical Oxygen Demand levels of 8500mg/L, and unfortunately, it is often discarded back into the environment untreated. After decades of serious environmental damages, the Chinese government in 2016 decided to enforce strict pollution penalties, leading to production cuts and factory closures. Today, GlucosaGreen® undoubtedly represents an environmentally friendly option to shellfish glucosamine.
Glycomega™- PLUS is a scientifically researched blend of Greenshell™ mussel extract sourced from the clean waters of New Zealand and a botanical antioxidant, which together provide significant levels of anti-inflammatory activity.
|Aroma New Zealand|
Golden Omega Fish Oils are high quality Omega3 concentrates up to 75% of EPA and DHA obtained from sustainable sources in South America.
Golden Omega facilities are located in the north of Chile close to Corpesca’s fish oil plants. Corpesca is one of the principal fishing company in Chile and one of the most important worldwide. They are also one of the owner companies of Golden Omega together with Orizon which secures a continuous supply of fresh fish oil manufactured under high quality standards.
Golden Omega range includes: 33/22, 10/50, 36/24, 40/20, 34/26, 45/10. Ethyl Ester (EE) and Triglyceride (TG) forms available. The following high concentration forms have been recently added to the range: 460180EE, 360240EE, 170430EE, 360240TG, 440100TG and 410190TG.
|GO-TAB||WHY FISH OIL IN A TABLET?|
It allows Golden Omega Fish Oil Concentrates to be combined with other ingredients in one convenient unit: the tablet. Tablets can be prepared in any size or shape and added color or taste, without compromising stability.
Golden Omega™ Fish Oil Concentrates are highly pure Omega-3 concentrates with up to 750mg/gEPA + DHA combined. All the crude oil used as raw material in Golden Omega´s production has been verified as “pure anchovy from the South Pacific Ocean”. Golden Omega’s manufacturing facility is strategically located in the middle of the richest fishing ground for anchovy in the world, and it is also vertically integrated from fisheries which guarantees control over the supply chain and full traceability from the fishing to the final Omega-3 product. The crude oil is sourced from selected Friend of the Sea and IFFO RS certified fishing companies in Chile and Peru.
The University spin-off company OmegaTri AS was founded in 2007, based on the idea that Omega-3 could be included in tablets by preparing complexes of omega-3 fatty acids and cyclic polyglucose. Since then, OmegaTri™ has developed a technological platform allowing direct compressible (DC) grade powders comprising healthy lipids to be prepared. The main focus has been fish oils.
Tablets are the most stable and inexpensive application form available.
A great share of the global population avoids gelatin. An Omega-3 tablet represents an odor free, tasteless alternative without use of gelatin. Not all food supplement companies have a softgel production facility or can afford the minimum order quantities a soft gel contract manufacturer requires to run a production lot.Tablets represent the affordable and easily available alternative.
3 studies performed on reflux (available on request) – no fishy aftertaste reported.
Significantly shorter time to reach maximum concentration of EPA and DHA were observed for Omega-3 formulated in a tablet: results in studies suggested that uptake of lipids from tablets is less dependent on simultaneous food intake. High Oxidative Stability: The molecular encapsulation of each lipid molecule by cyclic polyglucose ensures a product stable to oxidation, therefore providing an attractive shelf-life.
|Golden Omega - |
Aging slows down the metabolism of cells and Hyaluronic acid (HA) synthesis in our body is decreased. As a result, there is not enough water in the collagenous fiber and elastic fiber of the skin, thus wrinkles appear. Because of the loss of HA within the synovial fluid of joints, it can lead to osteoarthritis. The synthesis and degradation of HA in the body is a dynamic balanced process. It is proved by numerous studies that oral intake of HA can increase the precursors of HA and promote its synthesis. Therefore, oral administration of HA can increase endogenetic HA and help achieve health and beauty from within.
Beauty from within: A 2016 study conducted in Spain with 29 volunteers for a period of 6 months demonstrated that oral supplementation of HAPLEX®Plus was effective in nourishing skin, with statistically significant results on the parameters of elasticity.
Joint Health: In a 6 months’ study conducted on 29 volunteers (2016), 150mg of HAPLEX®Plus and 800mg of Chondroitin Sulphate (CS) were administrated orally. The study demonstrated that HAPLEX®Plus and CS may help to improve the symptoms of osteoarthritis and, as the dose of CS was below the therapeutical levels, it was concluded that the effectiveness in this study was mainly due to HAPLEX®Plus.
It is not about how much curcumin is consumed, it is about how much is absorbed into the bloodstream, and what it does when it reaches target tissues.
ABOUT SLCP™ TECHNOLOGY (SOLID-LIPID CURCUMIN PARTICLE™)
SLCP™ Technology (US Patent 9192644, EU Patent 1993365, additional patents pending) is a safe, natural composition that promotes absorption of free curcumin into the bloodstream and various organs. Longvida®’s SLCP™ composition is precisely set in a way that protects the curcumin from the harsh environment of the stomach, offering efficacious amounts of free curcumin at easily managed daily doses. SLCP™ delivers free curcumin by meeting the critical requirements of permeability, solubility, and stability.
Longvida® is scientifically proven to be 67-285 times more bioavailable depending on cMAX, AUC, and AUC Normalized calculations than standard 95% curcumin. Longvida® offers therapeutic levels of free (not deactivated/metabolized or glucuronidated) curcumin, and has been clinically substantiated for blood brain barrier and blood retinal barrier permeability. Longvida® is effective, supporting nervous system function with small dosages: One small, single daily dose of Longvida® offered significant health benefits in just 30 days. A trial on Longvida® showed people reported cognitive function improvement using low-dose Longvida®. In another human trial, a single dose of Longvida® in humans has shown the ability to bind to brain aging-related aggregates (ie amyloid-beta). The curcumin found in Longvida® is natural and generally recognized as safe (self-GRAS). Daily dosing with Longvida® has had no reports of gastrointestinal irritation, as high amounts of curcuma longa are no longer needed.
In clinical studies, Longvida® showed a positive safety profile at doses of 8-12 grams (8,000-12,000 milligrams) per day. Longvida® showed no acute high-dose toxicity at the highest dose tested, a dose equivalent to 100 times the recommended dose. Longvida® does not contain piperine or volatile oils.
Longvida® has been studied for various health applications, including nervous system support, and promotion of longevity and cognitive health. Longvida® may help promote joint health and help to modulate inflammatory responses already within the normal range. Curcumin is also a potent antioxidant and is used in skin products as an anti-microbial and healing agent.
Muscle recovery, equine data, cardiovascular, brain, joint health, cognitive/mood, sports nutrition, retinal/ eye health, and others.
Clinically substantiated dose, 400mg once daily.
Naticol® is a type I fish collagen peptide, produced by enzymatic hydrolysis. It is a mixture of peptides with various molecular weights including some dipeptides and tripeptides. It is made from fish skin and scales.
The manufacturer carefully selects the raw material and enzyme mixture that generate peptides with targeted biological activities. The nature of the matrix is due to the raw material source, the choice of protease and the extent of hydrolysis which are the three main factors in the production of peptides with targeted biological activities.
Naticol fish collagen is also bioavailable, sustainable and safe. Initial clinical studies have been done on Naticol® to evaluate its benefits on skin and joint pain.
Typically taken as a tablet or capsule, there is a growing interest in consuming your daily requirement in a beverage form. We are now able to offer collagen as a blend with flavours and sweeteners (to your requirement) which can be used in a ready form for your instant drink (powder) or RTD. Optimised for excellent flavour characteristics our blends offer a simple route to product formulation for this growing sector.
Naticol® is also available as a standard powder (high and low molecular weight) or premium granular grade (Naticol® Premium HPMG and Naticol® Premium BPMG). The HPMG and BPMG Premium grades were developed to offer greater advantages to the most demanding customers’ applications. They are microgranulated and present excellent organoleptic properties (odourless and tasteless).
Making the most of the endless natural resources found in the Sardinia Island to offer high quality & innovative natural botanical extracts: This is the mission of Nating, an Italian company specialised in spray dried, granular, organic certified, liquid and glyceric natural extracts, with full traceability and total control of the supply chain and production cycle. Each botanical extract is the result of years of research and maximum attention to every stage of production, from the seed selection to the raw material extraction.
OptiMSM® is a branded form of MSM precisely manufactured in the U.S. in a single-purpose production facility. MSM is a bio-available source of sulphur and methyl groups benefiting human health.
OptiMSM® is manufactured by MSM experts Bergstrom Nutrition who offer a consistently high quality ingredient through:
• A dedicated plant that reduces the risk of cross-contamination and singular focus.
• FSSC 22,000 certification; this program is recognized by the Global Food Safety Initiative (GFSI) Board and incorporates GMP compliance and a HACCP plan.
• Purifying the product through a proprietary four stage distillation process.
The prestigious medical journal, Osteoarthritis and Cartilage, published a peer reviewed, double-blind, placebo-controlled study that showed MSM is safe and effective in increasing joint comfort and supporting a normal range of motion. OptiMSM® was used in the clinical trials.
Optimsm is available in microprill for tablets and capsules and flakes for powders, creams and functional beverages.
Pomella® extract is a patented, clinically researched pomegranate extract developed in collaboration with a major research university located in California. Standardized to punicalagins (which are water-soluble and highly bioavailable) along with the natural spectrum of pomegranate fruit polyphenols.
PureSea® is a natural, whole-food, organic, proprietary milled seaweed, sourced from the pristine sea lochs of the Scottish Outer Hebrides.
The seaweed is supplied by Seaweed & Co., and produced to sustainable and high quality standards using distinct techniques and technologies, and accredited by an expert panel.
|Seaweed and Co.|
Targeting the companion animal market PurforMSM® provides consumer’s confidence that their animals are receiving premium MSM free from contaminants.
PurforMSM® complies with the EU definition of Feed Material per Commission Regulation 575/2011, Section 13.9.1.
BIOTECHNOLOGY INGREDIENTS FROM GNOSIS
Improving the quality of life of humans and animals and promoting their well-being is the specific target of worldwide advanced nutrition. Following these major global trends and challenges Gnosis Bio can offer a unique range of raw materials produced from fermentation and patented biotechnology.
Below is an overview of their major brands:
In recent years evidence has shown the advantages of reduced folate vs folic acid. The rational use of such reduced folates (particularly reduced and methylated) is derived from the inability of a part of World’s population to assimilate and metabolize folic acid from food or supplements due to defects in an enzyme in the body which is required to convert folic acid and dietary folate to a form utilised by the body. Quatrefolic®enters the metabolic pathway at a later stage and is able to immediately provide the essential form used and stored in the human body, giving improved bioavailability with no risk to human health. Methyl folates in the calcium salt form can have limited stability and can require cold storage conditions. A second limiting factor is that their bioavailability is also reduced as a consequence of their low solubility properties. Quatrefolic® is a new generation of derived folate made up of (6S)-5-methyltetra-hydrofolate and glucosamine salt which is able to overcome the existing calcium salt form limitations related to stability, poor solubility and bioavailability. This new source of folate has four key critical factors that make it a successful ingredient: Bioavailability, safety, stability and formulation flexibility. In a crossover comparative bioavailability study carried out in healthy volunteers, Quatrefolic® has proven to be superior to the reference, (6S)-5-methyltetrahydrofolic calcium salt.
VitaMK7 is a naturally derived and solvent-free vitamin K2, obtained through a patent granted bio-fermentation process of Bacillus subtilis natto cultures. Developed and produced according to cGMP in a pharmaceutical approved manufacturing facility, Gnosis’ Menaquinone-7 is available commercially under the brand names of VitaMK7™ and K2&Olive™. The Vitamin K in VitaMK7™ consists entirely of all-trans Menaquinone-7. Gnosis uses supercritical CO2 technology to produce vitaMK7™ which leads to a concentrated oil extract or to a highly enriched biomass. This technique is consistent with the corporate goal of working in accordance with green chemistry principles. The supercritical CO2 method has been shown to have superior yield when compared to vitamin K2 extraction by conventional solvents, such as ethanol, methanol and isopropanol. The use of CO2 extraction method makes it possible to obtain MK-7 with a purity of the all-trans isomer higher than 99%.
Mythocondro®is the first Non-Animal Chondroitin Sulfate produced by a patented fermentation-based manufacturing process. The result of this innovative approach is a non-animal CS with homogeneous structure and a constant charge density and molecular mass parameters, like in animal synovial fluid and compliant to USP monograph of Chondroitin Sulfate Sodium. Furthermore, Mythocondro® production can guarantee high purity levels, clear identity profile, batch-to-batch reproducibility and established safety with an astounding very low content of proteins and other (macro) molecules.
There are more ingredients available from the Gnosis range. Contact our sales team for more information.
Biootic is a probiotic (Saccharomyces boulardii) acting as a temporary flora to protect intestinal tract and good bacteria in the intestine. Capable of surviving gastric acidity and able to resist all commonly used antibiotics, it is clinically recognized for its efficacy both, to preserve flora in the intestinal tract and to prevent and treat diarrhea events in all age groups, including children.
|US Greens|| ||US Greens|
VitaFiber™ IMO provides functionality of a soluble dietary fiber and a low calorie sweetener. It is naturally rich in fiber, has a mild, sweet flavor and a reduced calorie impact.
|BioNutra North America Inc.|
|Vitamin D Organic|| ||Guzen Development|
KatraPhytochem is a growing company established in 1996, focused on segregation, isolation, purification and formulation of carotenoids from different bio sources that are highly purified to meet the global Nutraceutical market.
KatraPhytochem represents an exceptional source for high quality nutraceutical ingredients, such as XanMax® a patented combination of natural lutein and zeaxanthin, and many more.
XanMax® is more than lutein: it is a unique combination of free lutein with varying levels of zeaxanthin, manufactured from carefully selected marigold plants.
In addition to XanMax® and thanks to our partnership with KatraPhytochem across Europe, we can also offer:
Lutein esters in powder, beadlets and oil (different concentrations)
Zeaxanthin in powder, beadlets and oil (different concentrations)